External factors: | NAC |
Aging type: | Prevent |
Aging characteristic: |
Category: | Chemical compounds |
Phenotype: | Aging |
Experiment: | SA-β-gal activity assay//SAHF//Western blot |
Description: | The results show that AAPH dramatically increased the SA β-Gal activity in A375 and NIH3T3 cells, which was significantly suppressed by NAC.AAPH caused robust SAHF formation in A375 cells,which was significantly reduced by NAC .Co-treatment with NAC reversed the AAPH-induced activation of the p53-p21 pathway. |
Regulatory pathway: | -- |
R-EF-Pathway: | -- |
Pathway experiment: | -- |
Pathway description: | -- |
Annotation: