Aging Overview

External factors

External factors: NAC
Aging type: Prevent
Aging characteristic:
Category: Chemical compounds
Phenotype: Aging
Experimental category: L
Tissue type: --
Cell name: A375,NIH-3T3
PMID: 30555576
Experiment: SA-β-gal activity assay//SAHF//Western blot
Description: The results show that AAPH dramatically increased the SA β-Gal activity in A375 and NIH3T3 cells, which was significantly suppressed by NAC.AAPH caused robust SAHF formation in A375 cells,which was significantly reduced by NAC .Co-treatment with NAC reversed the AAPH-induced activation of the p53-p21 pathway.


Regulatory pathway: --
R-EF-Pathway: --
Pathway experiment: --
Pathway description: --


Aging network

Annotation:

The green line represents Upregulation.

The purple line represents Downregulation.

The orange line represents Activation.

The yellow line represents Inhibition.

The gray line represents Unclear.