Aging Overview

External factors

External factors: Bleomycin
Aging type: Accelerate
Aging characteristic:
Category: Chemical compounds
Phenotype: Liver cancer
Experimental category: L
Tissue type: --
Cell name: U2OS
PMID: 24223226
Experiment: SA-β-gal activity assay//Cell morphological analysis
Description: Furthermore, another DNA damage-inducing drug bleomycin, which has a different mode of action from etoposide to induce DNA double-strand breaks, also induced premature senescence in U2OS cells.


Regulatory pathway: --
R-EF-Pathway: --
Pathway experiment: --
Pathway description: --


Aging network

Annotation:

The green line represents Upregulation.

The purple line represents Downregulation.

The orange line represents Activation.

The yellow line represents Inhibition.

The gray line represents Unclear.