Aging Overview

External factors

External factors: Bleomycin
Aging type: Accelerate
Aging characteristic:
Category: Chemical compounds
Phenotype: Aging
Experimental category: L
Tissue type: --
Cell name: HUVEC
PMID: 28064010
Experiment: SA-β-gal activity assay
Description: SA-β-galactosidase activity, as senescence marker in the cells .It has been shown that bleomycin could significantly induce HUVECs undergoing senescence in a dose- and time-dependent manner.


Regulatory pathway: --
R-EF-Pathway: --
Pathway experiment: --
Pathway description: --


Aging network

Annotation:

The green line represents Upregulation.

The purple line represents Downregulation.

The orange line represents Activation.

The yellow line represents Inhibition.

The gray line represents Unclear.