Aging Overview

External factors

External factors: Antioxidant
Aging type: Prevent
Aging characteristic:
Category: Chemical compounds
Phenotype: Aging
Experimental category: L
Tissue type: --
Cell name: NIH-3T3
PMID: 12134086
Experiment: SA-β-gal activity assay
Description: H2O2 alone (not in combination with quercetin) promoted the expression of senescence-associated β-galactosidase activity in NIH 3T3 cells. However, quercetin successfully prevented this H2O2-induced premature senescence.Treatment with vitamin E successfully prevented the H2O2-induced expression of acid β-galactosidase activity.


Regulatory pathway: --
R-EF-Pathway: --
Pathway experiment: --
Pathway description: --


Aging network

Annotation:

The green line represents Upregulation.

The purple line represents Downregulation.

The orange line represents Activation.

The yellow line represents Inhibition.

The gray line represents Unclear.