| External factors: | Atorvastatin |
| Aging type: | Prevent |
| Aging characteristic: |
| Category: | Chemical compounds |
| Phenotype: | Aging |
| Experiment: | Flow cytometry//PCR//SA-β-gal activity assay//Telomerase activity assay |
| Description: | Increase in ROS formation was significantly reduced by atorvastatin. Incubation with atorvastatin also inhibited the loss of intact mitochondrial DNA and abrogated the reduction of nuclear and overall TERT activity and protein. Furthermore, incubation with atorvastatin delayed the onset of senescence of endothelial cells . |
| Regulatory pathway: | -- |
| R-EF-Pathway: | -- |
| Pathway experiment: | -- |
| Pathway description: | -- |
Annotation: