| External factors: | H2O2 |
| Aging type: | Accelerate |
| Aging characteristic: |
| Category: | Chemical compounds |
| Phenotype: | Aging |
| Experiment: | SA-β-gal activity assay |
| Description: | To investigate whether our findings regarding TF inducibility were present in other forms of senescence, we exposed young HUVECs to 200 mM H2O2 for 2 h. This invoked stress-induced premature senescence (SIPS), which was manifested by growth arrest and positive staining for SA-β-gal in about 50% of cells . |
| Regulatory pathway: | -- |
| R-EF-Pathway: | -- |
| Pathway experiment: | -- |
| Pathway description: | -- |
Annotation: