Aging Overview

External factors

External factors: Doxorubicin
Aging type: Accelerate
Aging characteristic:
Category: Chemical compounds
Phenotype: Endometrioid adenocarcinoma
Experimental category: L
Tissue type: --
Cell name: HEC-1B,Ishikawa
PMID: 20372780
Experiment: SA-β-gal activity assay
Description: After the treatment with 0.1 μg/ml DOX for 120 h, among the cells that remained in the HEC-1B and Ishikawa cultures, 100% cells were β-galactosidase-positive. These data thus confirmed that treatment of cells of HEC-1B and Ishikawa lines with DOX for 120 h induces cell senescence in at least a portion of the population.




Aging network

Annotation:

The green line represents Upregulation.

The purple line represents Downregulation.

The orange line represents Activation.

The yellow line represents Inhibition.

The gray line represents Unclear.