| External factors: | Doxorubicin |
| Aging type: | Accelerate |
| Aging characteristic: |
| Category: | Chemical compounds |
| Phenotype: | Gastric cancer |
| Experiment: | SA-β-gal activity assay//Flow cytometry//SAHF//Cell morphological analysis |
| Description: | After treatment, most cells became flattened and had comparatively enlarged morphology. Positive level of senescence-associated SA-β-gal staining was increased in AGS cells; SAHF formation increased in treated MKN28 cells. Flow cytometry analysis demonstrated that proportions of cells in G0/G1 phase ncreased in treated cells. In MKN28 cells, we also noticed a significant increase in proportions of cells in G2/M . |
| Regulatory pathway: | -- |
| R-EF-Pathway: | -- |
| Pathway experiment: | -- |
| Pathway description: | -- |
Annotation: