Aging Overview

External factors

External factors: EGCG+SFN25
Aging type: Prevent
Aging characteristic:
Category: Chemical compounds
Phenotype: Colorectal cancer
Experimental category: L
Tissue type: --
Cell name: HT29
PMID: 17657594
Experiment: SA-β-gal activity assay
Description: HT-29 AP-1 cells, when cultured on cover slips and exposed to individual treatment of EGCG (20 or 100 mM) for 24 h, showed induction of senescence which was not observed in the case of SFN25 mM.Interestingly,on combining EGCG with SFN,the EGCG-associated senescence was attenuated.


Regulatory pathway: --
R-EF-Pathway: --
Pathway experiment: --
Pathway description: --


Aging network

Annotation:

The green line represents Upregulation.

The purple line represents Downregulation.

The orange line represents Activation.

The yellow line represents Inhibition.

The gray line represents Unclear.