Aging Overview

External factors

External factors: Doxorubicin
Aging type: Accelerate
Aging characteristic:
Category: Chemical compounds
Phenotype: Colorectal cancer
Experimental category: L
Tissue type: --
Cell name: HCT116,H1299
PMID: 29352261
Experiment: SA-β-gal activity assay//Flow cytometry
Description: Activation of the DNA damage response (DDR) pathway was accompanied by the appearance of such markers of senescence as increased SA-β-Gal activity and cell cycle arrest.


Regulatory pathway: --
R-EF-Pathway: --
Pathway experiment: --
Pathway description: --


Aging network

Annotation:

The green line represents Upregulation.

The purple line represents Downregulation.

The orange line represents Activation.

The yellow line represents Inhibition.

The gray line represents Unclear.