External factors: | Cilostazol |
Aging type: | Prevent |
Aging characteristic: |
Category: | Chemical compounds |
Phenotype: | Aging |
Experiment: | SA-β-gal activity assay |
Description: | Treatment with cilostazol inhibited the senescent phenotype induced by sirolimus or everolimus at 10 days. Under treatment with sirolimus or everolimus (2.5 nmol/l), 49.2% or 53.0% of cells were SA-βgal positive, versus only 13.6% or 14.6% of cilostazol (100 μmol/l)-treated cells under the same conditions. |
Regulatory pathway: | -- |
R-EF-Pathway: | -- |
Pathway experiment: | -- |
Pathway description: | -- |
Annotation: