| External factors: | Resveratrol |
| Aging type: | Accelerate |
| Aging characteristic: |
| Category: | Chemical compounds |
| Phenotype: | Cancer |
| Experiment: | SA-β-gal activity assay//Flow cytometry//Cell morphological analysis |
| Description: | Thus, in both cell lines, resveratrol induced the growth arrest, showing prominent feature of stress-induced senescence—an increased SA-β-galactosidase activity. Moreover, many cells in both lines increased in size showing enlarged nuclei—the morphology typical for the senescent cells (not shown). |
| Target gene: | BRCA1 |
| R-EF-Target gene: | Upregulation |
| Official symbol(s): | BRCA1 |
| Target gene experiment: | Western blot |
| Target gene description: | In A549 cells, the total amount of BRCA1 protein detected by D-9 antibody slightly increased between 6 and 30 h of treatment. |
| Regulatory pathway: | -- |
| R-EF-Pathway: | -- |
| Pathway experiment: | -- |
| Pathway description: | -- |
Annotation: