| External factors: | Rapamycin |
| Aging type: | Prevent |
| Aging characteristic: |
| Category: | Chemical compounds |
| Phenotype: | Glaucoma |
| Experiment: | Western blot//SA-β-gal activity assay |
| Description: | In this particular cell line, U0126 treatment by itself did not block phosphorylation of S6 and therefore caused senescent morphology,which was prevented by rapamycin. |
| Target gene: | CYCLIN D1 |
| R-EF-Target gene: | Downregulation |
| Official symbol(s): | CYCLIN D1 |
| Target gene experiment: | Western blot |
| Target gene description: | Although rapamycin moderately decreased PD0332991-induced cyclin D1, U0126 completely eliminated it. |
| Regulatory pathway: | -- |
| R-EF-Pathway: | -- |
| Pathway experiment: | -- |
| Pathway description: | -- |
Annotation: