External factors: | UVB irradiation |
Aging type: | Accelerate |
Aging characteristic: |
Category: | Other |
Phenotype: | Aging |
Experiment: | MTT assay//SA-β-gal activity assay |
Description: | Incremental doses of UVB cause cellular viability decline dose-dependently and at 296 to 696 mJ/cm2doses, the inhibitory effects were significant (P< 0.001);The proportion of positive β-galactosidase cells among UVB-irradiated cells was significantly (P < 0.01) greater than among non-irradiated ones. |
Target gene: | FOXO3A |
R-EF-Target gene: | Upregulation |
Official symbol(s): | FOXO3A |
Target gene experiment: | qPCR |
Target gene description: | UVB irradiation significantly upregulated the FOXO3A expression compared to the control cells . |
Regulatory pathway: | -- |
R-EF-Pathway: | -- |
Pathway experiment: | -- |
Pathway description: | -- |
Annotation: