| External factors: | Bleomycin |
| Aging type: | Accelerate |
| Aging characteristic: |
| Category: | Chemical compounds |
| Phenotype: | Aging |
| Experiment: | SA-β-gal activity assay//Cell morphological analysis |
| Description: | Bleomycin treatment induced the typical senescence alterations, including an enlarged morphology, increased SA-β-gal activity as well as a strong nuclear recruitment of pHP1c . |
| Target gene: | IKBζ |
| R-EF-Target gene: | Upregulation |
| Official symbol(s): | IKBζ |
| Target gene experiment: | qRT-PCR |
| Target gene description: | Importantly, the expression of IkBζ was increased 3.6-fold, indicating that upregulation of IkBζ is independent of the senescence-inducing stimulus. |
| Regulatory pathway: | -- |
| R-EF-Pathway: | -- |
| Pathway experiment: | -- |
| Pathway description: | -- |
Annotation: