| External factors: | Doxycycline |
| Aging type: | Accelerate |
| Aging characteristic: |
| Category: | Chemical compounds |
| Phenotype: | Aging |
| Experiment: | SA-β-gal activity assay//Western blot |
| Description: | Doxycycline treatment resulted not only in a strong induction of RasG12V, but concomitantly induced senescence alterations including increased p21 expression, SA-β-gal activity and the characteristic pHP1c staining . |
| Target gene: | IKBζ |
| R-EF-Target gene: | Upregulation |
| Official symbol(s): | IKBζ |
| Target gene experiment: | qRT-PCR |
| Target gene description: | The expression of the senescence markers was again associated with a strongly increased IkBζ expression. |
| Regulatory pathway: | -- |
| R-EF-Pathway: | -- |
| Pathway experiment: | -- |
| Pathway description: | -- |
Annotation: