Aging Overview

External factors

External factors: Radiation
Aging type: Accelerate
Aging characteristic:
Category: Other
Phenotype: Aging
Experimental category: L
Tissue type: --
Cell name: HUVEC
PMID: 30616437
Experiment: SA-β-gal activity assay
Description: HUVECs treated with low doses of ionizing radiation showed a significant increase in SA-β-gal+ cells in a dose-dependent manner (p?


Regulatory relationship

Target gene: KU86//P16
R-EF-Target gene: Downregulation//Upregulation
Official symbol(s): KU86//P16
Target gene experiment: Western blot
Target gene description: We also found that the increased ionization caused a significant reduction in Ku86 expression and a significant increase in p16Ink4a expression in a dose-dependent manner.

Regulatory pathway: --
R-EF-Pathway: --
Pathway experiment: --
Pathway description: --


Aging network

Annotation:

The green line represents Upregulation.

The purple line represents Downregulation.

The orange line represents Activation.

The yellow line represents Inhibition.

The gray line represents Unclear.