Aging Overview

External factors

External factors: Adhesion molecule on glia
Aging type: Accelerate
Aging characteristic:
Category: Other
Phenotype: Glioma
Experimental category: HL
Tissue type: --
Cell name: U87 MG
PMID: 31510944
Experiment: SA-β-gal activity assay//Knockdown
Description: β-galactosidase activity was reduced in the group treated with AMOG siRNA as compared with the Control group as seen with single cells and cell aggregates.


Regulatory relationship

Target gene: L1
R-EF-Target gene: --
Official symbol(s): L1
Target gene experiment: Western blot
Target gene description: AMOG siRNA reduced AMOG expression (p = 0.0041) and increased L1 expression (p = 0.0029) in comparison to the Control siRNA group in U-87 MG cells .

Regulatory pathway: --
R-EF-Pathway: --
Pathway experiment: --
Pathway description: --


Aging network

Annotation:

The green line represents Upregulation.

The purple line represents Downregulation.

The orange line represents Activation.

The yellow line represents Inhibition.

The gray line represents Unclear.