External factors: | Lipid lowering therapy |
Aging type: | Prevent |
Aging characteristic: |
Category: | Other |
Phenotype: | Coronary artery disease |
Experiment: | FISH |
Description: | The aggressive LLT group showed reduced LDL cholesterol levels in CAD patients after 12 months of therapy. |
Target gene: | MIR-23A//TRF2 |
R-EF-Target gene: | Downregulation//Upregulation |
Official symbol(s): | MIR-23A//TERF2 |
Target gene experiment: | qRT-RCR//Flow cytometry |
Target gene description: | Aggressive LLT markedly decreased levels of miR-23a (2.78±1.29 vs. 2.09 ±1.17, P < 0.01) and increased levels of TRF2 (2.98 ± 1.44 vs.3.52 ± 1.34, P < 0.01). |
Regulatory pathway: | -- |
R-EF-Pathway: | -- |
Pathway experiment: | -- |
Pathway description: | -- |
Annotation: