| External factors: | DOX |
| Aging type: | Accelerate |
| Aging characteristic: |
| Category: | Chemical compounds |
| Phenotype: | Aging |
| Experiment: | SA-β-gal activity assay//Cell morphological analysis//SAHF |
| Description: | A significantly enlarged cell size, increased SA-β-gal activity, and increased SAHF in cells treated with 50 nM DOX for 4 days were noted. |
| Target gene: | MIR-375 |
| R-EF-Target gene: | Upregulation |
| Official symbol(s): | MIR-375 |
| Target gene experiment: | qRT-PCR |
| Target gene description: | By comparing miRNA expression profiles between treated and untreated K562 cells, 10 upregulated miRNAs were found in DOX-treated K562 cells .The expression of miR-375 remained to be the highest among the 4 miRNAs . |
| Regulatory pathway: | -- |
| R-EF-Pathway: | -- |
| Pathway experiment: | -- |
| Pathway description: | -- |
Annotation: