| External factors: | Lithium |
| Aging type: | Accelerate |
| Aging characteristic: |
| Category: | Other |
| Phenotype: | Cardiovascular disease |
| Experiment: | SA-β-gal activity assay |
| Description: | Lithium treatment for 5 days increased 4.5- fold the number of SA-β-galactosidase positive cells as compared with sodium-treated control cells. |
| Target gene: | MMP1//PAI-1 |
| R-EF-Target gene: | Upregulation//Upregulation |
| Official symbol(s): | MMP1//SERPINE1 |
| Target gene experiment: | qRT-PCR |
| Target gene description: | Lithium treatment for 24 h resulted in a significant 13-fold increase of MMP-1 and a 2.7-fold increase of PAI-1 mRNA levels. |
| Regulatory pathway: | -- |
| R-EF-Pathway: | -- |
| Pathway experiment: | -- |
| Pathway description: | -- |
Annotation: