| External factors: | PMA |
| Aging type: | Accelerate |
| Aging characteristic: |
| Category: | Chemical compounds |
| Phenotype: | Aging |
| Experiment: | Cell morphological analysis//SA-β-gal activity assay |
| Description: | We found that PMA caused a large flat morphology with nucleoli enlargement and beta-Gal positivity . |
| Target gene: | P21//CYCLIN D1 |
| R-EF-Target gene: | Activation//Activation |
| Official symbol(s): | P21//CYCLIN D1 |
| Target gene experiment: | Western blot |
| Target gene description: | PMA rapidly activated ERK1/2 followed by p21 and cyclin D1 induction. |
| Regulatory pathway: | -- |
| R-EF-Pathway: | -- |
| Pathway experiment: | -- |
| Pathway description: | -- |
Annotation: