| External factors: | Ascorbic acid |
| Aging type: | Prevent |
| Aging characteristic: | Others |
| Category: | Chemical compounds |
| Phenotype: | Aging |
| Experiment: | Western blot//SA-β-gal activity assay |
| Description: | The increased expression of p16 induced by D-gal could be reduced when treated with ascorbic acid (AA).After adding AA,the SA-β-gal positive cells ratio could be decreased compared to D-gal only group. |
| Regulatory pathway: | Akt-mTOR |
| R-EF-Pathway: | Downregulation |
| Official symbol(s): | AKT1-MTOR |
| Pathway experiment: | Western blot |
| Pathway description: | Activation of AKT/mTOR signaling pathway was increased in the Dgal group, and weakened when AA was added . |
Annotation: