| External factors: | D-gal |
| Aging type: | Accelerate |
| Aging characteristic: | Others |
| Category: | Chemical compounds |
| Phenotype: | Aging |
| Experiment: | CCK-8 assay assay//Western blot//SA-β-gal activity assay |
| Description: | We found that cell survival rate was inhibited by D-gal in a time- and dose-dependent manner.The expression of p16 was gradually increased as the concentration raised.We found that SA-β-gal positive cells ratio was obviously increased by D-gal stimulation. |
| Regulatory pathway: | Akt-mTOR |
| R-EF-Pathway: | Upregulation |
| Official symbol(s): | AKT1-MTOR |
| Pathway experiment: | Western blot |
| Pathway description: | The expressions of p-AKT and p-mTOR were promoted by D-gal in a timeand dose-dependent manner. |
Annotation: