| External factors: | Metformin |
| Aging type: | Prevent |
| Aging characteristic: |
| Category: | Chemical compounds |
| Phenotype: | Aging |
| Experiment: | Western blot |
| Description: | Moreover, a declined p16 and p53 expression was also detected in the metformin-treated group, indicating that the senescence characteristics of the endogenous Alpl+/- MSCs were rescued by the metformin treatment. |
| Regulatory pathway: | AMPK |
| R-EF-Pathway: | Activation |
| Official symbol(s): | AMPK |
| Pathway experiment: | Western blot |
| Pathway description: | The expression levels of p-AMPKα and p-ACC were elevated in the Alpl+/- MSCs after the metformin injections . |
Annotation: