| External factors: | Extracellular vesicles |
| Aging type: | Prevent |
| Aging characteristic: |
| Category: | Other |
| Phenotype: | Aging |
| Experiment: | SA-β-gal activity assay |
| Description: | DOX greatly increased βgal positive cells, which was significantly ameliorated by human serum EVs treatment. |
| Regulatory pathway: | miR-34a-PNUTS |
| R-EF-Pathway: | -- |
| Official symbol(s): | MIR34A-PPP1R10 |
| Pathway experiment: | qPCR |
| Pathway description: | In H9C2 cells, we found that EVs significantly decreased the expression level of miR-34a.Our study also found that miR-34a mimic downregulated PNUTS expression in H9C2 cells, while miR-34a inhibitor significantly elevated that. |
Annotation: