External factors: | Autophagy |
Aging type: | Accelerate |
Aging characteristic: |
Category: | Other |
Phenotype: | Aging |
Experiment: | SA-β-gal activity assay//Western blot |
Description: | 3-MA and LY also inhibited CDKN1A and CDKN2A upregulation as well as SA-GLB1/β-gal activity in serum-starved fibroblasts. |
Regulatory pathway: | MTORC2 |
R-EF-Pathway: | Activation |
Official symbol(s): | ARMH4 |
Pathway experiment: | SA-β-gal activity assay//Western blot |
Pathway description: | Serum-starved fibroblasts exposed to R showed lowered CDNK1A and CDKN2A protein levels and decreased SA-GLB1/β-gal activity .RPTOR silencing led, however, to inhibition of SA-GLB1/β-gal activity. |
Annotation: