| External factors: | LY294002 |
| Aging type: | Prevent |
| Aging characteristic: |
| Category: | Chemical compounds |
| Phenotype: | Aging |
| Experiment: | SA-β-gal activity assay//Cell morphological analysis |
| Description: | LY294002 decreased intensity of SA-β-Gal staining but did not abrogate it completely . Cells remained flat, with a typical nuclear appearance.LY294002 suppressed senescence. |
| Regulatory pathway: | mTOR-S6 |
| R-EF-Pathway: | Downregulation |
| Official symbol(s): | MTOR |
| Pathway experiment: | Western blot |
| Pathway description: | Like rapamycin, LY294002 inhibited S6 phosphorylation at day 1 . |
Annotation: