| External factors: | Phenolic diterpenes carnosic acid |
| Aging type: | Prevent |
| Aging characteristic: |
| Category: | Chemical compounds |
| Phenotype: | Aging |
| Experiment: | MTT assay//SA-β-gal activity assay |
| Description: | The pre-incubation with CA conferred a significant protection against H2O2-induced cell growth inhibition and the appearance of SA-β-gal positive cells. |
| Regulatory pathway: | Nrf2 |
| R-EF-Pathway: | Upregulation |
| Official symbol(s): | NFE2L2 |
| Pathway experiment: | Western blot |
| Pathway description: | AS increased the levels of Nrf2 in the nuclear fraction.Treatment of ASF-2 cells with CA significantly increased the transcriptional activity of Nrf2. |
Annotation: