| External factors: | Ginsenoside Rg3 |
| Aging type: | Accelerate |
| Aging characteristic: |
| Category: | Chemical compounds |
| Phenotype: | Glioma |
| Experiment: | SA-β-gal activity assay |
| Description: | ~67% of U87 cells after chronic 20(S)-Rg3 treatment at a 20 M concentration were stained positively compared with only ~5% cells with positive staining in the DMSO control group. |
| Regulatory pathway: | p53-p21//Akt |
| R-EF-Pathway: | Upregulation//Activation |
| Official symbol(s): | TP53-CDKN1A//AKT1 |
| Pathway experiment: | Western blot |
| Pathway description: | The treatment of U87 cells with 20(S)-Rg3 significantly increased the expression levels of p53 and p21.U87 cells treated with 20 M 20(S)-Rg3 were characterized by increases in phosphoAkt. |
Annotation: