| External factors: | HIV |
| Aging type: | Accelerate |
| Aging characteristic: |
| Category: | Other |
| Phenotype: | Aging |
| Experiment: | Western blot//SA-β-gal activity assay |
| Description: | Infection of VSVG-HIV also caused a 1.8-fold increase in p16INK4Alevels .Transfection of HFAs with HIVBal plasmid induced SA‐β-Gal+ cells from 8% in pcDNA3 control plasmid to 20% in HIV‐transfected cells. |
| Regulatory pathway: | β-catenin |
| R-EF-Pathway: | Downregulation |
| Official symbol(s): | CTNNBIP1 |
| Pathway experiment: | Western blot//SA-β-gal activity assay |
| Pathway description: | HIV also inhibited β-catenin signaling in HFA, as demonstrated by inhibition of Activate β-catenin expression post-VSVG-HIV infection to 30% at 48 h and 22% at 72 h of the VSVG control. |
Annotation: