Aging Overview

External factors

External factors: Resveratrol
Aging type: Prevent
Aging characteristic:
Category: Chemical compounds
Phenotype: Preterm
Experimental category: L
Tissue type: --
Cell name: PT-ECFC
PMID: 24518759
Experiment: Western blot//Immunofluorescence
Description: RSV induced a gradual decrease in p16INK4aexpression in time-dependent manner;We found that RSV treatment of PT-ECFCs postponed the G0/G1 arrest.


Regulatory relationship

Target gene: SIRT
R-EF-Target gene: Upregulation
Official symbol(s): SIRT
Target gene experiment: RT-PCR
Target gene description: RSV increased SIRT1 gene expression in a time-dependent manner which correlated with accumulation of Activate chromatin marks at the SIRT1 promoter.

Regulatory pathway: --
R-EF-Pathway: --
Pathway experiment: --
Pathway description: --


Aging network

Annotation:

The green line represents Upregulation.

The purple line represents Downregulation.

The orange line represents Activation.

The yellow line represents Inhibition.

The gray line represents Unclear.