| External factors: | NaHS |
| Aging type: | Prevent |
| Aging characteristic: |
| Category: | Chemical compounds |
| Phenotype: | Aging |
| Experiment: | SA-β-gal activity assay//SAHF |
| Description: | Treatment with NaHS decreased the percentage of SA-β-gal positive cells.The strongest effect was observed when NaHS was at 50 lmol/L.Treatmentwith NaHS (12.5, 25 and 50 lmol/L) decreased the expression of SAHF the strongest effect was found when NaHS was at 50 lmol/L. |
| Target gene: | SIRT1 |
| R-EF-Target gene: | Upregulation |
| Official symbol(s): | SIRT1 |
| Target gene experiment: | Western blot//RT-PCR |
| Target gene description: | NaHS/resveratrol could increase the expression of SIRT1 compared with Y﹢N group. It was found that the mRNA expression of SIRT1 in Y﹢N group was significantly decreased compared with that in the young group, and NaHS reversed this effect. |
| Regulatory pathway: | -- |
| R-EF-Pathway: | -- |
| Pathway experiment: | -- |
| Pathway description: | -- |
Annotation: