| External factors: | OX-LDL |
| Aging type: | Accelerate |
| Aging characteristic: |
| Category: | Chemical compounds |
| Phenotype: | Cardiovascular disease |
| Experiment: | SA-β-gal activity assay |
| Description: | As the concentrations of OX-LDL increased, the number of β-galactosidase-positive cells increased significantly, reaching a maximal value at 100 mg/mL OX-LDL. |
| Target gene: | SIRT1 |
| R-EF-Target gene: | Downregulation |
| Official symbol(s): | SIRT1 |
| Target gene experiment: | Western blot |
| Target gene description: | At this concentration of OX-LDL, the SIRT1 protein expression was significantly decreased as compared to control cells. |
| Regulatory pathway: | -- |
| R-EF-Pathway: | -- |
| Pathway experiment: | -- |
| Pathway description: | -- |
Annotation: