| External factors: | Losartan |
| Aging type: | Prevent |
| Aging characteristic: |
| Category: | Chemical compounds |
| Phenotype: | Aging |
| Experiment: | SA-β-gal activity assay//Flow cytometry |
| Description: | Pretreatment with losartan decreased the percentage of SA-β-gal positive cells, reversed the distribution of cells at each phase. |
| Target gene: | STAT1 |
| R-EF-Target gene: | Downregulation |
| Official symbol(s): | STAT1 |
| Target gene experiment: | Western blot |
| Target gene description: | Pretreatment with losartan reduced the expression of STAT1, phosphorylation of STAT1, and phosphorylation of p53, p53, and p21Cip1. |
| Regulatory pathway: | -- |
| R-EF-Pathway: | -- |
| Pathway experiment: | -- |
| Pathway description: | -- |
Annotation: