External factors: | Resveratrol |
Aging type: | Accelerate |
Aging characteristic: |
Category: | Chemical compounds |
Phenotype: | Glioma |
Experiment: | SA-β-gal activity assay//Cell morphological analysis |
Description: | Resveratrol induced dramatic changes in cell volume and cell morphology in both U87 and U118 cells. Specifically, resveratrol transformed spindle-shaped glioma cells to enlarged and irregular flattenshaped ones.SA-β-gal was detected in these hypertrophic cells. |
Target gene: | UH2B |
R-EF-Target gene: | Downregulation |
Official symbol(s): | UH2B |
Target gene experiment: | Western blot |
Target gene description: | Resveratrol inhibited uH2B within 4 h in a dose-dependent manner. |
Regulatory pathway: | -- |
R-EF-Pathway: | -- |
Pathway experiment: | -- |
Pathway description: | -- |
Annotation: