External factors: | CRT0063465 |
Aging type: | Prevent |
Aging characteristic: |
Category: | Chemical compounds |
Phenotype: | Hypoglycemia |
Experiment: | Southern blot |
Description: | Strikingly, however, despite the lack of effects observed on total cellular telomerase activity by CRT0063465, hypoglycemic erosion of telomeres was blocked in the presence of the compound at both 100 nM and 10 nM. |
Target gene: | PGK1//DJ1 |
R-EF-Target gene: | --//-- |
Official symbol(s): | PGK1//PARK7 |
Target gene experiment: | Co-IP |
Target gene description: | For PGK1, 10 nM CRT0063465 increased telomere association under physiological glucose conditions.For DJ1, compound treatment did not significantly affect telomere association under physiological conditions. |
Regulatory pathway: | -- |
R-EF-Pathway: | -- |
Pathway experiment: | -- |
Pathway description: | -- |
Annotation: