External factors: | Resveratrol |
Aging type: | Prevent |
Aging characteristic: |
Category: | Chemical compounds |
Phenotype: | Aging |
Experiment: | SA-β-gal activity assay |
Description: | Resveratrol influenced EPCs senescence dose dependently, with a maximal inhibitory effect achieved at 50mM. |
Target gene: | TELOMERASE |
R-EF-Target gene: | Activation |
Official symbol(s): | TELOMERASE |
Target gene experiment: | Western blot |
Target gene description: | Resveratrol dose dependently increased telomerase activity, with a maximal increase at 50mM. |
Regulatory pathway: | PI3K-Akt |
R-EF-Pathway: | -- |
Official symbol(s): | PIK3CB-AKT |
Pathway experiment: | Western blot |
Pathway description: | Stimulation with resveratrol led to dose-dependent phosphorylation of Akt, although it did not affect the total amount of Akt. |
Annotation: