| External factors: | Resveratrol |
| Aging type: | Prevent |
| Aging characteristic: |
| Category: | Chemical compounds |
| Phenotype: | Aging |
| Experiment: | SA-β-gal activity assay//Colony formation assay |
| Description: | SA-β-gal activity significantly increased in LP-MSCs compared with that in EP-MSCs(SIRT1 expression) treated with either EtOH or with resveratrol.The CFU-F assay was performed. The results showed that resveratrol enhanced the colony-forming ability of EP-MSCs. |
| Target gene: | β-CATENIN |
| R-EF-Target gene: | Downregulation |
| Official symbol(s): | β-CATENIN |
| Target gene experiment: | Western blot |
| Target gene description: | Western blot results showed that in EP-MSCs, ERK phosphorylation was reduced by resveratrol, resulting in a decrease of Activate β-catenin (non-phosphorylated). |
| Regulatory pathway: | ERK |
| R-EF-Pathway: | Downregulation |
| Official symbol(s): | ERK |
| Pathway experiment: | Western blot |
| Pathway description: | Western blot results showed that in EP-MSCs, ERK phosphorylation was reduced by resveratro. |
Annotation: