Aging Overview

Aging gene

Gene name: NFKBIA
Aging type: Prevent
Aging characteristic:
Tissue type: --
Cell name: HDFs
Gene ID: 4792
Category: protein coding
Phenotype: Aging
Experimental category: HL
PMID: 33459422
Experiment: RNA-seq//GO analysis
Description: The transcriptome of non‐irradiated NFKBIA‐depleted cells shared a strong overlap and the same GO terms with the senescent cells of the second phase.IκBα rescue through ectopic overexpression of an NFKBIA mutant encoding the proteasome‐insensitive IκBαS32AS36A blocked the induction of the bona fide SASP factors.


Regulatory pathway: --
R-AG-Pathway: --
Pathway experiment: --
Pathway description: --


Aging network

Annotation:

The green line represents Upregulation.

The purple line represents Downregulation.

The orange line represents Activation.

The yellow line represents Inhibition.

The gray line represents Unclear.



About risk SNP and eQTL

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