Aging Overview

Aging gene

Gene name: HBP1
Aging type: Accelerate
Aging characteristic:
Tissue type: --
Cell name: NP Cells
Gene ID: 26959
Category: protein coding
Phenotype: Intervertebral disc degeneration
Experimental category: L
PMID: 32964956
Experiment: RT-qPCR
Description: The upregulation of HBP1 also af?fected collagen II expression and contributed to ?the rise of p16 expression.The ?HPB1 also triggered the IL-6, TNF, and MMP-3 ?expressions compared to the control. However, the silencing of HBP1 restrained the p16 expression and protected the collagen II level secreted by NP cells.


Regulatory pathway: --
R-AG-Pathway: --
Pathway experiment: --
Pathway description: --


Aging network

Annotation:

The green line represents Upregulation.

The purple line represents Downregulation.

The orange line represents Activation.

The yellow line represents Inhibition.

The gray line represents Unclear.



About risk SNP and eQTL

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