| Gene name: | SENEX |
| Aging type: | Accelerate |
| Aging characteristic: |
| Tissue type: | -- |
| Cell name: | OCI‐LY8 |
| Gene ID: | 93663 |
| Category: | protein coding |
| Phenotype: | r/r DLBCL |
| Experimental category: | L |
| PMID: | 33015970 |
| Experiment: | SA-β-gal activity assay |
| Description: | Interestingly, compared with the control group (C group) and scramble negative control (NC group), the senescence rate and proliferation rate were significantly decreased (Figure 5C–G), but the apoptosis rate was significantly increased in SENEX silenced group (SS group). |
| Regulatory pathway: | P16-RB |
| R-AG-Pathway: | Activation |
| Pathway experiment: | Western blot |
| Pathway description: | We found that p16 ?and pRB expression levels were both significantly increased after the induction of doxorubicin, while RB ?expression level was decreased. |
Annotation:
Loading,please wait...