Aging Overview

Aging gene

Gene name: HES1
Aging type: Prevent
Aging characteristic:
Tissue type: Skin
Cell name: Dermal fibroblasts
Gene ID: 3280
Category: protein coding
Phenotype: Aging
Experimental category: HL
PMID: 33238152
Experiment: SA-β-gal activity assay//Clonal expansion assay
Description: Ectopic overexpression or CRISPR-dCas9-mediated endogenous activation of HES1 protected human fibroblasts against aging phenotypes, evidenced by increased cell proliferation and attenuated cell senescence


Regulatory pathway: --
R-AG-Pathway: --
Pathway experiment: --
Pathway description: --


Aging network

Annotation:

The green line represents Upregulation.

The purple line represents Downregulation.

The orange line represents Activation.

The yellow line represents Inhibition.

The gray line represents Unclear.



About risk SNP and eQTL

Loading,please wait...