Aging Overview

Aging gene

Gene name: CARTPT
Aging type: Prevent
Aging characteristic:
Tissue type: Cortex
Cell name: Primary cortical neurons
Gene ID: 9607
Category: protein coding
Phenotype: AD
Experimental category: L
PMID: 33610183
Experiment: Western blot//qRT-PCR
Description: The western blotting results indicated that p16, TNFα and IL-1β protein expression levels were significantly increased in Aβ1–42-treated primary cortical neurons, but were significantly decreased following pretreatment with CART. Furthermore, RT-qPCR results demonstrated that p16, p53, IL-6 and IL-1β mRNA expression levels were significantly increased in Aβ1–42-treated primary cortical neurons, but were significantly decreased following pretreatment with CART. SOD1 protein and SOD2 mRNA expression levels were significantly decreased in the Aβ1–42-treated primary cortical neurons, but were significantly increased following pretreatment with CART.


Regulatory pathway: --
R-AG-Pathway: --
Pathway experiment: --
Pathway description: --


Aging network

Annotation:

The green line represents Upregulation.

The purple line represents Downregulation.

The orange line represents Activation.

The yellow line represents Inhibition.

The gray line represents Unclear.



About risk SNP and eQTL

Loading,please wait...