Gene name: | CARTPT |
Aging type: | Prevent |
Aging characteristic: |
Tissue type: | Cortex |
Cell name: | Primary cortical neurons |
Experiment: | Western blot//qRT-PCR |
Description: | The western blotting results indicated that p16, TNFα and IL-1β protein expression levels were significantly increased in Aβ1–42-treated primary cortical neurons, but were significantly decreased following pretreatment with CART. Furthermore, RT-qPCR results demonstrated that p16, p53, IL-6 and IL-1β mRNA expression levels were significantly increased in Aβ1–42-treated primary cortical neurons, but were significantly decreased following pretreatment with CART. SOD1 protein and SOD2 mRNA expression levels were significantly decreased in the Aβ1–42-treated primary cortical neurons, but were significantly increased following pretreatment with CART. |
Regulatory pathway: | -- |
R-AG-Pathway: | -- |
Pathway experiment: | -- |
Pathway description: | -- |
Annotation:
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