| Gene name: | MFN2 |
| Aging type: | Accelerate |
| Aging characteristic: |
| Tissue type: | -- |
| Cell name: | Chondrocyte |
| Gene ID: | 9927 |
| Category: | protein coding |
| Phenotype: | Osteoarthritis |
| Experimental category: | L |
| PMID: | 32416221 |
| Experiment: | SA-β-gal activity assay//flow cytometry |
| Description: | Representative microscopy images of senescence-associated b-galactosidase activity. Flow cytometry analysis of mitochondrial ROS level of NC and siMfn2#3 chondrocytes. |
| Target gene: | PARKIN |
| Official symbol(s): | PARKIN |
| R-AG-Target gene: | Downregulation |
| Subcategory: | Ubiquitylation |
| Target gene experiment: | Western blot//Co-IP |
| Target gene description: | The protein expression of PARKIN, MFN2 in NC siRNA, PARKIN siRNA#1, #2, #3-treated chondrocytes. Chondrocytes were immunoprecipitated with anti-MFN2 or control IgG, the immunoprecipitated complex was detected by Western blotting with anti-PARKIN. |
| Regulatory pathway: | -- |
| R-AG-Pathway: | -- |
| Pathway experiment: | -- |
| Pathway description: | -- |
Annotation:
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