| Gene name: | NSD2 |
| Aging type: | Prevent |
| Aging characteristic: |
| Tissue type: | -- |
| Cell name: | IMR-90 |
| Experiment: | SA-β-gal activity assay//flow cytometry |
| Description: | Cell cycle analysis by propidium iodide staining revealed that the population of cells in G2/M phase was slightly increased on day 6 in NSD2-KD cells. Furthermore, NSD2-depleted cells exhibited SA-β-Gal staining starting on day 3 after siRNA transfection. |
| Regulatory pathway: | RB |
| R-AG-Pathway: | -- |
| Pathway experiment: | Knockdown |
| Pathway description: | Knockdown of RB completely abolished the reduced expression of RB-associated genes such as MCM3, LMNB1, and EZH2 in NSD2-KD cells. |
Annotation:
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