Aging Overview

Aging gene

Gene name: ERG
Aging type: Prevent
Aging characteristic:
Tissue type: --
Cell name: LNCaP
Gene ID: 2078
Category: protein coding
Phenotype: Aging
Experimental category: HL
PMID: 32674955
Experiment: SA-β-gal activity assay
Description: Analysis of cellular senescence by senescence-associated (SA)-b-galactosidase (Gal) activity measurement in LNCaP cells after treatment with 0.5 mM daunorubicin or DMSO as control.


Regulatory relationship

Target gene: P53
Official symbol(s): P53
R-AG-Target gene: Upregulation
Subcategory: Unclear
Target gene experiment: Western blot//Immunofluorescence microscopy
Target gene description: Protein levels of p53 and ERG in control vector and DN-ERG transfected normal human prostatic epithelial cells (hPREC) and LNCaP cells were analyzed by immunoblotting. ERG and p53 expression were evaluated by immunofluorescence microscopy in LNCaP cells transfected with control vector or DN-ERG for 48 h.

Regulatory pathway: --
R-AG-Pathway: --
Pathway experiment: --
Pathway description: --


Aging network

Annotation:

The green line represents Upregulation.

The purple line represents Downregulation.

The orange line represents Activation.

The yellow line represents Inhibition.

The gray line represents Unclear.



About risk SNP and eQTL

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