Aging Overview

Aging gene

Gene name: LMNA
Aging type: Prevent
Aging characteristic:
Tissue type: --
Cell name: HSF,MEF
Gene ID: 4000
Category: protein coding
Phenotype: HGPS
Experimental category: L
PMID: 32813328
Experiment: SA-β-gal activity assay//Western blot
Description: Representative images of SA-βGal staining in HSFs (P17) treated with the indicated siRNAs. Western blot analysis of METTL14, p21, and p16 levels in MEFs (P3) treated with the indicated siRNAs.


Regulatory relationship

Target gene: METTL3/14
Official symbol(s): METTL3/14
R-AG-Target gene: Upregulation
Subcategory: Unclear
Target gene experiment: Co-IP//Western blot
Target gene description: Co-IP and Western blot analysis of the endogenous interaction between Lamin A and METTL14 and Lamin A and METTL3 in MEFs.

Regulatory pathway: --
R-AG-Pathway: --
Pathway experiment: --
Pathway description: --


Aging network

Annotation:

The green line represents Upregulation.

The purple line represents Downregulation.

The orange line represents Activation.

The yellow line represents Inhibition.

The gray line represents Unclear.



About risk SNP and eQTL

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