Aging Overview

Aging gene

Gene name: CDKN2B-AS1
Aging type: Prevent
Aging characteristic:
Tissue type: --
Cell name: HEK293T,HTM
Gene ID: 100048912
Category: ncRNA
Phenotype: POAG
Experimental category: HL
PMID: 32825664
Experiment: SA-β-gal activity assay//PCR
Description: The human cellular senescence and extracellular matrix and adhesion molecules RT2 Profiler PCR arrays showed differential gene expression profile in TM cells after 10 nM CDKN2B-AS1 siRNA and control siRNA treatment for 72 h. Senescence-relatedβ-galactosidase staining of TM cells after 10 nM CDKN2B-AS1 siRNA and control siRNA treatment.


Regulatory relationship

Target gene: CDKN2B
Official symbol(s): CDKN2B
R-AG-Target gene: Downregulation
Subcategory: Unclear
Target gene experiment: immunocytochemistry//RT-PCR
Target gene description: A marked increase in CDKN2B expression was also observed in TM cells after 10 nM CDKN2B-AS1 siRNA treatment as assessed by immunocytochemistry and RT-PCR.

Regulatory pathway: --
R-AG-Pathway: --
Pathway experiment: --
Pathway description: --


Aging network

Annotation:

The green line represents Upregulation.

The purple line represents Downregulation.

The orange line represents Activation.

The yellow line represents Inhibition.

The gray line represents Unclear.



About risk SNP and eQTL

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