Aging Overview

Aging gene

Gene name: ATG5
Aging type: Prevent
Aging characteristic:
Tissue type: --
Cell name: NPCs
Gene ID: 9474
Category: protein coding
Phenotype: Intervertebral disc degeneration
Experimental category: L
PMID: 33921398
Experiment: Western blot//SA-β-gal activity assay
Description: IL-1β-increased percentage of senescence-associated beta-galactosidase (SA-β-gal)-positive cells. Increased p16/INK4A, p21/WAF1/CIP1, and p53 expression, indicating senescence induction.


Regulatory pathway: --
R-AG-Pathway: --
Pathway experiment: --
Pathway description: --


Aging network

Annotation:

The green line represents Upregulation.

The purple line represents Downregulation.

The orange line represents Activation.

The yellow line represents Inhibition.

The gray line represents Unclear.



About risk SNP and eQTL

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